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Bromodomain Testis-specific Protein (BrdT), human recombinant

A protein driving meiotic and post-meiotic gene expression program
Catalog #: 7641
SKU-Size Size Price Qty
7641-20 20 µg
7641-100 100 µg
7641-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
Gene Symbol BRDT
Gene ID 676
Accession # Q58F21
Source E. coli
Appearance Liquid
Physical Form Description rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Molecular Weight 13.9 kDa (117aa, 22-138 +NT-His Tag)
Purity by SDS-PAGE ≥98%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans.


BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVision’s recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag.

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