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Briciclib

A suppressor cyclin D1 accumulation in cancer cells
Catalog #: B1140

In stock

SKU-Size Size Price Qty
B1140-5 5 mg
$165.00
B1140-25 25 mg
$625.00
More Sizes Get Quote

Product Details

Alternate Name [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
Appearance White Solid
CAS # 865783-99-9
Molecular Formula C₁₉H₂₃O₁₀PS
Molecular Weight 474.42
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
InChi 1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
InChi Key LXENKEWVEVKKGV-BQYQJAHWSA-N
PubChem CID 11248490
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells. Cyclin D, a member of the cyclin family of cell cycle regulators, plays a key role in cell cycle division and is often overexpressed in a variety of hematologic and solid tumors and is correlated with poor prognosis.


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