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BRD7116

A leukemia stem cell (LSC) inhibitor
Catalog #: B1578

In stock

SKU-Size Size Price Qty
B1578-5 5 mg
$165.00
B1578-25 25 mg
$650.00

Product Details

Alternate Name N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Appearance White solid
CAS # 329059-55-4
Molecular Formula C₂₈H₃₆N₂O₄S
Molecular Weight 496.66
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml) or EtOH (>10 mg/ml)
SMILES CC1(C(C1(C)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)C4C(C4(C)C)(C)C)C
InChi InChI=1S/C28H36N2O4S/c1-25(2)21(26(25,3)4)23(31)29-17-9-13-19(14-10-17)35(33,34)20-15-11-18(12-16-20)30-24(32)22-27(5,6)28(22,7)8/h9-16,21-22H,1-8H3,(H,29,31)(H,30,32)
InChi Key UHXFWAHRAMUDLJ-UHFFFAOYSA-N
PubChem CID 981129
MDL Number MFCD02168947
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BRD 7116 is a selective inhibitor of leukemia stem cell (LSC) activity (EC₅₀ value of 200 nM). BRD 7116 does not affect normal hematopoietic stem cells or AML cell lines (EC₅₀s = 20 µM).


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