A selective inhibitor of HDAC1 and 2
Catalog #: B2931 | abID:

Product Details

Alternate Name 4-(Acetylamino)-N-[2-amino-5-(2-thienyl)phenyl]-benzamide; Compound 60; TPB; HDAC1 & 2 Inhibitor
Appearance Solid
CAS # 849234-64-6
Molecular Formula C₁₉H₁₇N₃O₂S
Molecular Weight 351.42
Purity 97%
Solubility 2 mg/ml in in DMSO
InChi InChI=1S/C19H17N3O2S/c1-12(23)21-15-7-4-13(5-8-15)19(24)22-17-11-14(6-9-16(17)20)18-3-2-10-25-18/h2-11H,20H2,1H3,(H,21,23)(H,22,24)
PubChem CID 349358485
MDL Number MFCD16495786
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


BRD6929 is a benzamide-based brain-penetrant inhibitor of Histone deacetylases HDAC1 and HDAC2. It increases histone acetylation and inhibits HDAC1 and HDAC2 with an IC₅₀ of 1 nM and 8 nM respectively. It shows 50–400 fold selectivity over HDAC3 with an IC₅₀ of 458 nM. Chronic treatment with BRD6929 improves mood-related behaviors in mice.

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