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An inhibitor of histone methyltransferase G9a
Catalog #: 9525
SKU-Size Size Price Qty
9525-5 5 mg
9525-25 25 mg
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Product Details

Alternate Name Methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate
Appearance White to off-white solid
CAS # 1374601-40-7
Molecular Formula C₂₅H₂₃N₃O₃
Molecular Weight 413.47
Purity ≥98% by HPLC
Solubility DMSO(10 mg/ml)
InChi InChI=1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)
PubChem CID 72193870
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BRD4770 is a selective inhibitor of the histone methyltransferase G9a (also named euchromatin histone methyltransferase 2 (EHMT2). BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apoptosis. In addition, it induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1.

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