A PTP and PTEN inhibitor
Catalog #: 1793 | abID: ab141436

Product Details

abID ab141436
Cat # +Size 1793-5
Size 5 mg
Alternate Name Potassium bisperoxo(1,10-phenanthroline)oxovanadate (V)
Appearance Yellow to orange solid
CAS # 42494-73-5
Molecular Formula K[VO(O₂)₂C₁₂H₈N₂].3H₂O
Molecular Weight 404.3
Purity ≥98% by ⁵¹V-NMR
Solubility DMSO or H₂O
SMILES C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O.O.O.[OH-].OO.OO.[K+].[V]
InChi InChI=1S/C12H8N2.K.2H2O2.4H2O.V/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;2*1-2;;;;;/h1-8H;;2*1-2H;4*1H2;/q;+1;;;;;;;/p-1
PubChem CID 16760322
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also an excellent insulin mimetic in vitro and in vivo and a potent PTEN inhibitor (IC₅₀ = 38 nM).

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Jia Liu. miR-338-3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and ß-catenin signaling pathways. Mol Med Rep May-19. 31115502.
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