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BPTES

An allosteric glutaminase (GLS1) inhibitor
Catalog #: B2165

In stock

SKU-Size Size Price Qty
B2165-5 5 mg
$115.00
B2165-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name N,N'-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide
Appearance White solid
CAS # 314045-39-1
Molecular Formula C₂₄H₂₄N₆O₂S₃
Molecular Weight 524.68
Purity ≥98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES C1=CC=C(C=C1)CC(=O)NC2=NN=C(S2)CCSCCC3=NN=C(S3)NC(=O)CC4=CC=CC=C4
InChi InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-
InChi Key MDJIPXYRSZHCFS-UHFFFAOYSA-N
PubChem CID 3372016
MDL Number MFCD01079848
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BPTES is an allosteric glutaminase (GLS1) inhibitor (IC₅₀ = 3.3 μM). Displays selectivity for GLS1 over GLS2 and γ-glutamyl transpeptidase. Induces cell death of P493 human lymphoma B cells in vitro and reduces tumor volume of P493 cell xenografts in mice.


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