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A CDC25 Phosphatase Inhibitor I
Catalog #: B2371

In stock

SKU-Size Size Price Qty
B2371-5 5 mg
B2371-25 25 mg
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Product Details

Alternate Name Phenol, 4-(dimethylamino)-2-methoxy-6-((methyl(2-(4-nitrophenyl)ethyl)amino)methyl)-, CDC25 Phosphatase Inhibitor I, BN82002, PTP Inhibitor XX
Appearance Off-white solid
CAS # 396073-89-5
Molecular Formula C₁₉H₂₅N₃O₄
Molecular Weight 359.43
Purity ≥98% by HPLC
Solubility >50 mg/ml in DMSO
SMILES CN(C)C1=CC(=C(C(=C1)CN(C)CCC2=CC=C(C=C2)[N+](=O)[O-])O)OC
InChi InChI=1S/C19H25N3O4/c1-20(2)17-11-15(19(23)18(12-17)26-4)13-21(3)10-9-14-5-7-16(8-6-14)22(24)25/h5-8,11-12,23H,9-10,13H2,1-4H3
PubChem CID 9798923
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BN-82002 is a cell-permeable CDC25 Phosphatase Inhibitor. BN-82002 is a potent, cell-permeable, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively). BN-82002 inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro. It impairs the proliferation of tumoral cell lines and increases cyclin-dependent kinase 1 inhibitory tyrosine phosphorylation.

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