Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

BN-82002

A CDC25 Phosphatase Inhibitor I
Catalog #: B2371

In stock

SKU-Size Size Price Qty
B2371-5 5 mg
$115.00
B2371-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name Phenol, 4-(dimethylamino)-2-methoxy-6-((methyl(2-(4-nitrophenyl)ethyl)amino)methyl)-, CDC25 Phosphatase Inhibitor I, BN82002, PTP Inhibitor XX
Appearance Off-white solid
CAS # 396073-89-5
Molecular Formula C₁₉H₂₅N₃O₄
Molecular Weight 359.43
Purity ≥98% by HPLC
Solubility >50 mg/ml in DMSO
SMILES CN(C)C1=CC(=C(C(=C1)CN(C)CCC2=CC=C(C=C2)[N+](=O)[O-])O)OC
InChi InChI=1S/C19H25N3O4/c1-20(2)17-11-15(19(23)18(12-17)26-4)13-21(3)10-9-14-5-7-16(8-6-14)22(24)25/h5-8,11-12,23H,9-10,13H2,1-4H3
InChi Key GOKYHQGRIIXMNE-UHFFFAOYSA-N
PubChem CID 9798923
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BN-82002 is a cell-permeable CDC25 Phosphatase Inhibitor. BN-82002 is a potent, cell-permeable, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively). BN-82002 inhibits the phosphatase activity of recombinant human CDC25A, B, and C in vitro. It impairs the proliferation of tumoral cell lines and increases cyclin-dependent kinase 1 inhibitory tyrosine phosphorylation.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.