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BMS-813160

A potent KCa1.1 (BK) channel opener
Catalog #: B3332
SKU-Size Size Price Qty
B3332-5 5 mg
$165.00
B3332-25 25 mg
$650.00
More Sizes Get Quote

Product Details

Alternate Name N-[(1R,2S,5R)-5-[(1,1-Dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]acetamide BMS813160
Appearance Solid
CAS # 1286279-29-5
Molecular Formula C₂₅H₄₀N₈O₂
Molecular Weight 484.6
Purity ≥98%
Solubility DMSO
SMILES CC(C)(C)C1=NN2C(N=CN=C2N[[email protected]]3CCN([[email protected]]4([H])[[email protected]](NC(C)=O)C[[email protected]](NC(C)(C)C)CC4)C3=O)=C1
InChi InChI=1S/C25H40N8O2/c1-15(34)28-18-12-16(30-25(5,6)7)8-9-19(18)32-11-10-17(22(32)35)29-23-27-14-26-21-13-20(24(2,3)4)31-33(21)23/h13-14,16-19,30H,8-12H2,1-7H3,(H,28,34)(H,26,27,29)/t16-,17+,18-,19+/m1/s1
InChi Key CMVHFGNTABZQJU-HCXYKTFWSA-N
PubChem CID 51039119
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMS-191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1). Acts as a neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke).


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