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BMS-191011

A potent KCa1.1 (BK) channel opener
Catalog #: B3331
SKU-Size Size Price Qty
B3331-5 5 mg
$135.00
B3331-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name BMS191011 1,3,4-Oxadiazol-2(3H)-one, 3-((5-chloro-2-hydroxyphenyl)methyl)-5-(4-(trifluoromethyl)phenyl)-
Appearance White solid
CAS # 202821-81-6
Molecular Formula C₁₆H₁₀ClF₃N₂O₃
Molecular Weight 370.71
Purity ≥98%
Solubility >30 mg/ml DMSO
SMILES OC1=CC=C(Cl)C=C1CN1N=C(OC1=O)C1=CC=C(C=C1)C(F)(F)F
InChi InChI=1S/C16H10ClF3N2O3/c17-12-5-6-13(23)10(7-12)8-22-15(24)25-14(21-22)9-1-3-11(4-2-9)16(18,19)20/h1-7,23H,8H2
InChi Key QKOWACXSXTXRKA-UHFFFAOYSA-N
PubChem CID 10474339
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMS-191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1). Acts as a neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke).


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