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A potent BTK (Bruton's Tyrosine Kinase) inhibitor
Catalog #: B2791
SKU-Size Size Price Qty
B2791-1 1 mg
B2791-5 5 mg
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Product Details

Alternate Name 7-(2-hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxoquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1231889-53-4
Molecular Formula C₃₁H₂₆N₄O₃
Molecular Weight 502.56
Purity ≥98%
Solubility >100 mg/ml DMSO
InChi InChI=1S/C31H26N4O3/c1-17-19(8-6-10-26(17)35-16-33-24-9-5-4-7-22(24)30(35)37)20-13-14-23(29(32)36)28-27(20)21-12-11-18(31(2,3)38)15-25(21)34-28/h4-16,34,38H,1-3H3,(H2,32,36)
PubChem CID 70647728
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor (IC50 = 2.8 nM). It is more potent against BTK than other kinases, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.

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