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A potent partial LXR agonist
Catalog #: B2602
SKU-Size Size Price Qty
B2602-5 5 mg
B2602-25 25 mg
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Product Details

Alternate Name 2-(2-(2-(2-chlorophenyl)propan-2-yl)-1-(3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-4-yl)propan-2-ol, BMS 779788, EXEL04286652, XL652, BMS779788, EXEL-04286652, XL-652
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 918348-67-1
Molecular Formula C₂₈H₂₉ClN₂O₃S
Molecular Weight 509.06
Purity ≥98% by HPLC
Solubility in DMSO
SMILES CC(C)(C1=CC=CC=C1Cl)C2=NC(=CN2C3=CC=C(C=C3)C4=CC(=CC=C4)S(=O)(=O)C)C(C)(C)O
InChi InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(2
PubChem CID 59251511
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BMS-779788 is a LXR partial agonist with IC₅₀ values of 68 nM for LXRα and 14 nM for LXRβ. BMS-779788 induces LXR target genes in blood in vivo with an EC₅₀ = 610 nM, a value similar to its in vitro blood gene induction potency.

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