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BMP-7, human recombinant

A protein involved in the transformation of mesenchymal cells into bone and cartilage
Catalog #: 4579

In stock

SKU-Size Size Price Qty
4579-10 10 μg
$180.00
4579-50 50 μg
$495.00
4579-1000 1 mg
$3,950.00
More Sizes Get Quote

Product Details

Alternate Name Osteogenic Protein 1, BMP-7
Gene Symbol BMP 7
Gene ID 655
Accession # P18075
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 15.7 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity BioVision’s recombinant human BMP-7 is biologically active. The ED₅₀ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Reconstitution Instructions Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-7 produced from E. coli is a 15.7 kDa monomeric, non-glycosylated, polypeptide chain containing 139 amino acid residues.


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