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BMP-5, human recombinant

A protein involved in bone and cartilage development
Catalog #: 4574
SKU-Size Size Price Qty
4574-10 10 μg
$180.00
4574-50 50 μg
$295.00
4574-1000 1 mg
$2,950.00
More Sizes Get Quote

Product Details

Alternate Name Bone morphogenetic protein 5, BMP-5, BMP5, MGC34244
Gene Symbol BMP5
Gene ID 653
Accession # P22003
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 31.0 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent induction of alkaline phosphatase production with ATDC5 chondrogenic cells is typically 0.3-3 µg/ml.
Reconstitution Instructions Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20° for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

BMPs (bone morphogenetic proteins) belong to the TGF-βsuperfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Human BMP-5 is a 31 kDa homodimeric protein consisting of two 134 amino acid polypeptide chains.


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