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BMP-4 Antibody

Catalog #: 5674R
SKU-Size Size Price Qty
5674R-30T 30 µg
$89.00
5674R-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target BMP-4
Alternate Name BMP4, BMP-4, BMP 4, bone morphogenetic protein 4, BMP2B, BMP2B1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 395 of human BMP-4
Accession # P12644
Gene ID 652
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat, chicken, rabbit
Application Western blot, Immunohistochemistry
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), sμggesting that BMP-4 may play a role in activation of the Smad pathway.


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