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Product Details
| Antibody Target | BMP-4 |
|---|---|
| Alternate Name | BMP-4, BMP4, BMP 4,BMP-4 Polyclonal Antibody, Anti-BMP-4 Polyclonal antibody, BMP-4 beta antibody, Anti-BMP-4, BMP, Bone Morphogenetic Protein, BMPs |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant human BMP-4 expressed from E. coli |
| Accession # | AAC72278 |
| Gene ID | 652 |
| Appearance | Colorless liquid |
| Concentration | 0.2 mg/ml |
| Formulation | 100 µg (0.2 mg/ml) affinity purified anti-BMP-4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | Western blot |
| Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), sμggesting that BMP-4 may play a role in activation of the Smad pathway.
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