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BMP-4 Antibody

Catalog #: 5674A
SKU-Size Size Price Qty
5674A-30T 30 µg
$89.00
5674A-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target BMP-4
Alternate Name BMP-4, BMP4, BMP 4,BMP-4 Polyclonal Antibody, Anti-BMP-4 Polyclonal antibody, BMP-4 beta antibody, Anti-BMP-4, BMP, Bone Morphogenetic Protein, BMPs
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant human BMP-4 expressed from E. coli
Accession # AAC72278
Gene ID 652
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) affinity purified anti-BMP-4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), sμggesting that BMP-4 may play a role in activation of the Smad pathway.


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