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BMP-3b/GDF-10, human recombinant

Has multiple roles in skeletal morphogenesis
Catalog #: 7303
$375.00

Product Details

Cat # +Size 7303-100
Size 100 μg
Alternate Name BMP-3b, BMP3B, BIP, Growth differentiation factor 10
Gene Symbol GDF10
Gene ID 2662
Accession # P55107
Source E. coli
Appearance Liquid
Physical Form Description In 10 mM sodium citrate (pH 3.5) containing 10% glycerol
Molecular Weight 12.5 kDa (111 aa, 369-478 aa), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.


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