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BMP-3 Antibody

Catalog #: 5673R

In stock

SKU-Size Size Price Qty
5673R-30T 30 µg
$89.00
5673R-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target BMP-3
Alternate Name BMP-3 Polyclonal Antibody, Anti-BMP-3 Polyclonal antibody, BMP-3 beta antibody, Anti-BMP-3, BMP-3, BMP 3, BMP, Bone Morphogenetic Protein, BMPs, BMP3
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 369 of mouse BMP-3
Accession # P12645
Gene ID 651
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 30 µg (0.5 mg/ml) affinity purified anti-BMP-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). It detects the ~55 kDa full length and the ~16 kDa cleaved fragment of BMP-3. Blocking peptide (Cat.# 5673RBP-50) is available separately.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In vivo studies have shown that BMP-3 can independently induce cartilage formation.


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