Product Details
| Antibody Target | BMP-14 |
|---|---|
| Alternate Name | BMP-14, BMP14, BMP 14,BMP-14 Polyclonal Antibody, Anti-BMP-14 Polyclonal antibody, BMP-14 antibody, Anti-BMP-14, BMP, TGf-beta, Bone Morphogenetic Protein, BMPs |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant human BMP-14 precursor protein |
| Accession # | EAW76208 |
| Gene ID | 8200 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 30 µg (0.5 mg/ml) affinity purified rabbit anti-human BMP-14 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 1% BSA, 0.02% thimerosal. |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | Western blot, Immunohistochemistry |
| Positive Control | Western Blot: Recombinant human BMP-14 IHC: Brain and Cortex tissue |
| Application & Usage | Western blot analysis (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Recombinant human BMP-14 (Cat.# 4580-10) can be used as a positive control. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development.
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