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BMP-13, human recombinant

A TGF-beta family protein involved in patterning of the epidermis and bone & joint formation
Catalog #: 4639
SKU-Size Size Price Qty
4639-10 10 μg
$80.00
4639-50 50 μg
$190.00
4639-1000 1 mg
$1,450.00
More Sizes Get Quote

Product Details

Alternate Name bone morphogenetic protein 13, GDF-6, Cartilage-Derived Morphogenetic Protein-2, CDMP-2
Gene Symbol GDF6
Gene ID 392255
Accession # Q6KF10
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 27 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 µg/ml.
Reconstitution Instructions Reconstitute to 0.1-1.0 mg/ml in H₂O containing BSA (50 μg BSA per 1 μg of protein).
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. BioVision’s recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.


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