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BMP-11, human recombinant

A protein that controls anterior-posterior patterning by regulating the expression of Hox genes
Catalog #: 4576
SKU-Size Size Price Qty
4576-10 10 μg
$190.00
4576-50 50 μg
$330.00
4576-1000 1 mg
$2,975.00
More Sizes Get Quote

Product Details

Alternate Name bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 11
Gene Symbol BMP11/GDF11
Gene ID 10220
Accession # O95390
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 10 mM Sodium Citrate, pH 3.5.
Molecular Weight 32.6 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED₅₀ is in the range of 0.4-4 µg/ml.
Reconstitution Instructions Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 μg BSA per 1 μg of protein). This solution can then be diluted into other aqueous buffers.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-11 is N-terminus His-tagged protein with a molecular weight of 32.6 kDa (for homodimeric) and 16.2 (for monomeric) consisting of 136 amino acid polypeptide chains.


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