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BMP-10, human recombinant

A protein which is likely to be involved in the tabeculation of the heart
Catalog #: 4581
SKU-Size Size Price Qty
4581-1000 1 mg
$4,150.00
4581-20 20 μg
$190.00
4581-100 100 μg
$520.00
More Sizes Get Quote

Product Details

Alternate Name bone morphogenetic protein 10, BMP10, BMP 10
Gene Symbol BMP10
Gene ID 27302
Accession # O95393
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 32 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED₅₀ is in the range of 0.3-3 µg/ml.
Reconstitution Instructions Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-10 is essential for the proper development of the heart, but is not expressed until after cardiac patterning or looping are completed. Recombinant human BMP-10 is a 32 kDa disulfide-linked homodimer containing two 142 amino acid polypeptide chains.


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