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A potent and selective PARP1/2 inhibitor
Catalog #: B1861
SKU-Size Size Price Qty
B1861-1 1 mg
B1861-5 5 mg
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Product Details

Alternate Name (8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-1H-pyrido[4,3,2-de]phthalazin-3(2H)-one; Talazoparib
Appearance Crystalline solid
CAS # 1207456-01-6
Molecular Formula C₁₉H₁₄F₂N₆O
Molecular Weight 380.35
Purity ≥98% by HPLC
Solubility DMSO (>15 mg/ml)
InChi InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)
PubChem CID 53345055
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BMN-673 is a potent and selective PARP1/2 inhibitor with Ki values of 1.2 and 0.9 nM, respectively. It had no effect on panels of 72 receptors, ion channels, and enzymes. BMN-673 displays selective antitumor cytotoxicity and elicits DNA repair biomarkers at much lower concentrations than earlier generation PARP1/2 inhibitors.

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