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A potent FGFR4 inhibitor
Catalog #: B2359

In stock

SKU-Size Size Price Qty
B2359-1 1 mg
B2359-5 5 mg
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Product Details

Appearance White to off-white solid
CAS # 1707289-21-1
Molecular Formula C₂₄H₂₄Cl₂N₄O₄
Molecular Weight 503.38
Purity ≥98% by HPLC
Solubility >25 mg/ml (DMSO)
InChi InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15(14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8,12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1
PubChem CID 91885617
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BLU-554 is a potent inhibitor of recombinant fibroblast growth factor receptor 4 (FGFR4) IC₅₀ < 10 nM). It also inhibits phosphorylation of ERK (IC₅₀ < 10 nM), a marker of FGFR4 inhibition, in MDA-MB-453 breast cancer cells.

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