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A selective non-muscle myosin II ATPases inhibitor
Catalog #: 2405
SKU-Size Size Price Qty
2405-5 5 mg
2405-25 25 mg
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Product Details

Alternate Name (±)-1,​2,​3,​3a-​tetrahydro-​3a-​hydroxy-​6-​methyl-​1-​phenyl-​4H-​pyrrolo[2,​3-​b]quinolin-​4-​one
Appearance Yellow solid
CAS # 674289-55-5
Molecular Formula C₁₈H₁₆N₂O₂
Molecular Weight 292.34
Purity ≥98% by HPLC
Solubility DMSO (~25 mg/ml)
InChi InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3
PubChem CID 3476986
MDL Number MFCD04113775
Handling Protect from light and air
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC₅₀ = 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC₅₀ = 80 μM). Through these effects, blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.

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