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Blasticidin S Hydrochloride

based on 1 citations in multiple journalsBlasticidin S Hydrochloride14.1 4
A protein synthesis inhibitor
Catalog #: 1859
SKU-Size Size Price Qty
1859-25 25 mg
$160.00
1859-100 100 mg
$435.00
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Product Details

Alternate Name Blasticidine S
Appearance White to off-white solid
CAS # 3513-03-9
Molecular Formula C₁₇H₂₆N₈O₅ · HCl
Molecular Weight 458.9
Purity ≥98% by HPLC
Solubility H₂O
SMILES CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
InChi InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10+,13-,14+;/m1./s1
InChi Key YQXYQOXRCNEATG-ZAYJLJTISA-N
PubChem CID 25078183
MDL Number MFCD02091640
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Blasticidin S is a peptide nucleoside antibiotic that is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. It specifically inhibits protein synthesis in both prokaryotes and eukaryotes by interfering with the peptide bound formation in the ribosomal machinery.


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Shigeharu Ueki et al., Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. Blood, Mar 2013; 121: 2074 - 2083.
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