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Product Details
| Alternate Name | Blasticidine S |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 3513-03-9 |
| Molecular Formula | C₁₇H₂₆N₈O₅ · HCl |
| Molecular Weight | 458.9 |
| Purity | ≥98% by HPLC |
| Solubility | H₂O |
| SMILES | CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl |
| InChi | InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10+,13-,14+;/m1./s1 |
| InChi Key | YQXYQOXRCNEATG-ZAYJLJTISA-N |
| PubChem CID | 25078183 |
| MDL Number | MFCD02091640 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Blasticidin S is a peptide nucleoside antibiotic that is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. It specifically inhibits protein synthesis in both prokaryotes and eukaryotes by interfering with the peptide bound formation in the ribosomal machinery.
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Shigeharu Ueki et al., Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. Blood, Mar 2013; 121: 2074 - 2083.
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