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BIX 01294

A G9a histone lysine methyltransferase (HMTase) inhibitor
Catalog #: 1678
SKU-Size Size Price Qty
1678-5 5 mg
$130.00
1678-25 25 mg
$485.00
More Sizes Get Quote

Product Details

Alternate Name 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
Appearance Off-white solid
CAS # 935693-62-2
Molecular Formula C₂₈H₃₈N₆O₂
Molecular Weight 490.65
Purity ≥95% by HPLC
Solubility DMSO (10 mg/ml) or Ethanol (10 mg/ml)
SMILES CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC
InChi InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)
InChi Key OSXFATOLZGZLSK-UHFFFAOYSA-N
PubChem CID 25150857
MDL Number MFCD14560563
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.


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