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Product Details
| Alternate Name | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine |
|---|---|
| Appearance | Off-white solid |
| CAS # | 935693-62-2 |
| Molecular Formula | C₂₈H₃₈N₆O₂ |
| Molecular Weight | 490.65 |
| Purity | ≥95% by HPLC |
| Solubility | DMSO (10 mg/ml) or Ethanol (10 mg/ml) |
| SMILES | CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC |
| InChi | InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31) |
| InChi Key | OSXFATOLZGZLSK-UHFFFAOYSA-N |
| PubChem CID | 25150857 |
| MDL Number | MFCD14560563 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.
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