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Bisindolylmaleimide I

A Potent and ATP-competitive protein kinase C (PKC) inhibitor
Catalog #: 1945

In stock

SKU-Size Size Price Qty
1945-1 1 mg
$80.00
1945-5 5 mg
$305.00
More Sizes Get Quote

Product Details

Alternate Name 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide; GF 109203X; Gö 6850; BIM I
Appearance Orange solid
CAS # 133052-90-1
Molecular Formula C₂₅H₂₄N₄O₂
Molecular Weight 412.49
Purity ≥98% by NMR
Solubility DMSO (~ 10 mg/ml)
SMILES CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
InChi 1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)
InChi Key QMGUOJYZJKLOLH-UHFFFAOYSA-N
PubChem CID 2396
MDL Number MFCD00236428
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A Potent and ATP-competitive protein kinase C (PKC) inhibitor (Ki = 10 nM). Also acts as a potent Glycogen synthase kinase-3 (GSK-3) inhibitor.


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