Product Details
| Alternate Name | Biotin-6-aminohexanoic acid-N-hydroxysuccinimide ester; Biotin-X-NHS |
|---|---|
| Appearance | White solid |
| CAS # | 72040-63-2 |
| Molecular Formula | C₂₀H₃₀N₄O₆S |
| Molecular Weight | 454.54 |
| Purity | ≥95% by HPLC |
| Solubility | DMSO (20 mg/ml) or DMF (20 mg/ml) |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3 |
| InChi | InChI=1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1 |
| InChi Key | UVGHPGOONBRLCX-NJSLBKSFSA-N |
| PubChem CID | 83874 |
| MDL Number | MFCD00065502 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20 ̊C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Biotin-LC-NHS is a useful reagent for biotinylation of primary amines under alkaline conditions (pH~8-9). Some examples of primary amines for biotinylation include lysines on the surface of proteins, antibodies, etc. Inserts a 6-atom spacer between biotin and the target ligand, thus minimizing the steric hindrance.
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