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Biotin-LC-LC-NHS

A biotinylation agent for primary amines
Catalog #: 2346
SKU-Size Size Price Qty
2346-50 50 mg
$135.00
2346-250 250 mg
$495.00
2346-1000 1 g
$1,495.00
More Sizes Get Quote

Product Details

Alternate Name 6-((6-((Biotinoyl)amino)hexanoyl)amino)hexanoic acid, succinimidyl ester; Biotin-XX-NHS
Appearance White solid
CAS # 89889-52-1
Molecular Formula C₂₆H₄₁NO₇S
Molecular Weight 567.7
Purity ≥95% by HPLC
Solubility DMF (~ 25 mg/ml)
SMILES C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3
InChi InChI=1S/C26H41N5O7S/c32-20(27-16-8-2-4-12-24(36)38-31-22(34)13-14-23(31)35)10-3-1-7-15-28-21(33)11-6-5-9-19-25-18(17-39-19)29-26(37)30-25/h18-19,25H,1-17H2,(H,27,32)(H,28,33)(H2,29,30,37)/t18-,19-,25-/m0/s1
InChi Key ATYCFNRXENKXSE-MHPIHPPYSA-N
PubChem CID 16219024
MDL Number MFCD00467154
Handling Protect from air and moisture
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Biotin-LC-LC-NHS is a useful reagent for biotinylation of primary amines under mild conditions (pH~6.5-8.5). Some examples of primary amines for biotinylation include lysines on the surface of proteins, antibodies, etc. Inserts a 14-atom spacer between biotin and the target ligand, thus minimizing the steric hindrance in binding avidin or streptavidin to some biotinylated compounds and increase sensitivity for detection.


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