You have no items in your shopping cart.
Product Details
| Cat # +Size | E4870-100 |
|---|---|
| Size | 96 assays |
| Detection Method | Absorbance (450 nm) |
| Species Reactivity | Human |
| Applications | This Sandwich ELISA kit is used for in vitro qualitative determination of antibodies to Ramucirumab in human serum and plasma samples |
| Features & Benefits | • Assay Precision: Intra-Assay and Inter-Assay CV < 30%
• For in vitro qualitative determination of antibodies to Ramucirumab in human serum and plasma samples • Cross Reactivity: Except for Ramucirumab, there is no cross reaction with other therapeutic antibodies and native serum immunoglobins |
| Kit Components | • Microtiter Plate
• Positive Control • Negative Control • Assay Buffer • HRP-conjugate Probe • TMB substrate (Avoid light) • Stop Solution • Wash buffer (20X) • Plate sealers |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Ramucirumab is a fully human IgG1 monoclonal antibody that targets vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor that is expressed on endothelial cells. As a result, the antibody inhibits the interaction with its ligands (VEGF A, C, and D) and prevents VEGF-mediated proliferation, migration of endothelial cells, and angiogenesis. The antibody has been approved to treat advanced gastric cancer/gastro-esophageal junction (GEJ) adenocarcinoma, metastatic non-small lung carcinoma (NSLC), metastatic colorectal cancer (mCRC), and hepatocellular carcinoma (HCC). BioSim™ anti-Ramucirumab ELISA kit has been specifically developed to qualitatively determine antibodies to Ramucirumab in human serum and plasma samples. The ELISA kit is based on the sandwich principle. Controls and samples are incubated in the microtiter plate coated with the drug Ramucirumab. After incubation, the wells are washed and the enzymatic activity is detected by the addition of chromogen-substrate. The enzyme-substrate reaction is terminated with an acidic stop solution. The color developed is proportional to the amount of antibodies specific for Ramucirumab present in the samples and controls. The qualitative test results can be evaluated using cut-off value.
Why buy BioVision Products?
 |
 |
 |
 |
Innovation |
Affordability |
Global Presence |
Technical Support |
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways. |
BioVision is committed to providing the highest quality products at a competitive price. |
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery. |
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently. |
