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Biochanin A

A naturally occurring isoflavone phytoestrogen
Catalog #: B2794
SKU-Size Size Price Qty
B2794-50 50 mg
$65.00
B2794-250 250 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name 5,7-Dihydroxy-4′-methoxyisoflavone; Olmelin; 4′-Methylgenistein
Peptide Sequence N/A
Appearance Light yellow to orange powder
CAS # 491-80-5
Molecular Formula C₁₆H₁₂O₅
Molecular Weight 284.27
Purity ≥98% by HPLC
Solubility >50 mg/ml DMSO
SMILES COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O
InChi InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3
InChi Key WUADCCWRTIWANL-UHFFFAOYSA-N
PubChem CID 5280373
MDL Number MFCD00006839
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Biochanin A is an isoflavone phytoestrogen found in red clover that acts as a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. Also acts as a fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.


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