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Bikinin

A highly specific inhibitor for the 7 Arabidopsis GSK-3 like kinase
Catalog #: 2034
SKU-Size Size Price Qty
2034-10 10 mg
$70.00
2034-50 50 mg
$265.00
More Sizes Get Quote

Product Details

Alternate Name 4-((5-Bromo-2-pyridinyl)amino)-4-oxobutanoic acid; Arabidopsis GSK-3 Inhibitor
Appearance White solid
CAS # 188011-69-0
Molecular Formula C₉H₉BrN₂O₃
Molecular Weight 273.08
Purity ≥95% by HPLC
Solubility DMSO ( 5 mg/ml)
SMILES C1=CC(=NC=C1Br)NC(=O)CCC(=O)O
InChi InChI=1S/C9H9BrN2O3/c10-6-1-2-7(11-5-6)12-8(13)3-4-9(14)15/h1-2,5H,3-4H2,(H,14,15)(H,11,12,13)
InChi Key XFYYQDHEDOXWGA-UHFFFAOYSA-N
PubChem CID 647833
MDL Number MFCD00116442
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A highly specific inhibitor for the 7 Arabidopsis GSK-3 like kinase that activates brassinosteroid (BR) signaling downstream of the BR receptor. Bikinin directly binds the GSK3 BIN2 and acts as an ATP-competitive inhibitor. Furthermore, bikinin inhibits the activity of six other Arabidopsis GSK3s.


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