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BIBW2992 (Tovok)

An EGFR/HER2 inhibitor
Catalog #: 1616

In stock

SKU-Size Size Price Qty
1616-1 1 mg
1616-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name Tovok, Afatinib
Appearance Crystalline solid
CAS # 439081-18-2
Molecular Formula C₂₄H₂₅ClFN₅O₃
Molecular Weight 485.94
Purity ≥99%
Solubility DMSO
InChi InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
PubChem CID 10184653
MDL Number MFCD12407405
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


BIBW-2992 is a potent irreversible EGFR/HER2 inhibitor. The potency of BIBW-2992 on the EGFR and HER2 kinases revealed IC₅₀ values of 0.5 nM and 14 nM, respectively. BIBW-2992 is highly selective for these kinases and no additional inhibition of other kinases has been observed.

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