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A novel inhibitor of class I PI3K/mTOR
Catalog #: B1719
SKU-Size Size Price Qty
B1719-1 1 mg
B1719-5 5 mg
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Product Details

Alternate Name BGT226; BGT 226; BGT-226; NVP-BGT226; NVPBGT226; NVP BGT226; (Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one; 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
Appearance Solid
CAS # 1245537-68-1
Molecular Formula C₃₂H₂₉F₃N₆O₆
Molecular Weight 650.6
Purity >98%
Solubility DMSO
InChi InChI=1S/C28H25F3N6O2.C4H4O4/c1-35-24-16-33-22-6-3-17(18-4-8-25(39-2)34-15-18)13-20(22)26(24)37(27(35)38)19-5-7-23(21(14-19)28(29,30)31)36-11-9-32-10-12-36;5-3(6)1-2-4(7)8/h3-8,13-16,32H,9-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
PubChem CID 57336745
MDL Number MFCD22124895
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively.

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