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BF2649 hydrochloride

A potent, cell-permeable and selective histamine H3 receptor inverse agonist
Catalog #: B2279
SKU-Size Size Price Qty
B2279-10 10 mg
B2279-50 50 mg
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Product Details

Alternate Name 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine;hydrochloride; Pitolisant
Appearance Off-white solid
CAS # 903576-44-3
Molecular Formula C₁₇H₂₇Cl₂NO
Molecular Weight 332.31
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml) or H2O (>30 mg/ml)
InChi InChI=1S/C17H26ClNO.ClH/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19;/h7-10H,1-6,11-15H2;1H
PubChem CID 11551689
MDL Number MFCD09970745
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


BF2649 is a potent, cell-permeable and selective histamine H3 receptor inverse agonist (EC₅₀ = 1.5 nM, Ki = 0.16 nM). BF2649 displays nootropic effects in cognitive disorders; reduces locomotor hyperactivity induced by methamphetamine.

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