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Bexgliflozin (EGT1442)

A potent sodium-glucose cotransporter 2 (SGLT2) inhibitor
Catalog #: B1929
SKU-Size Size Price Qty
B1929-1 1 mg
$85.00
B1929-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name (3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; EGT1442; THR1442
Appearance Crystalline solid
CAS # 1118567-05-7 
Molecular Formula C₂₄H₂₉ClO₇
Molecular Weight 464.94
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl
InChi InChI=1S/C24H29ClO7/c25-19-8-3-15(24-23(29)22(28)21(27)20(13-26)32-24)12-16(19)11-14-1-4-17(5-2-14)30-9-10-31-18-6-7-18/h1-5,8,12,18,20-24,26-29H,6-7,9-11,13H2/t20-,21-,22+,23-,24+/m1/s1
InChi Key BTCRKOKVYTVOLU-SJSRKZJXSA-N
PubChem CID 25195624
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Bexagliflozin is a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC₅₀ values of 5.6 µM and 2 nM for human SGLT1 and SGLT2, respectively. Bexagliflozin dose-dependently reduces HbA(1c) and blood glucose concentration without affecting body mass or insulin level.


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