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Beta-Actin Antibody

based on 9 citations in multiple journalsBeta-Actin Antibody94.1 4
Catalog #: 3662
SKU-Size Size Price Qty
3662-30T 30 µg
$89.00
3662-100 100 µg
$280.00
More Sizes Get Quote

Product Details

Antibody Target Beta-Actin
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to residues around amino acid 10 of human Actin
Accession # P02570
Gene ID 60
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse
Application Western blot
Application & Usage Western blotting (0.5-2 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 45 kDa beta-Actin in samples from human and mouse origins. Reactivity to other species has not been tested.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Actin is expressed in all eukaryotic cells and is the major component of the cytoskeleton. At least six types of actin are present in mammalian tissues and fall into three classes. Alpha actin expression is limited to various types of muscle and it regulates contactile potentials for the muscle cells, whereas beta and gamma actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility.


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Adam W. Akerman, Elevated Wall Tension Leads to Reduced miR‐133a in the Thoracic Aorta by Exosome Release. J Am Heart Assoc., Dec. 2018,  30572760
Mizutani et al., Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.  J. Biochem., May 2015; 10.1093/jb/mvv039.
Saeki et al., Staurosporine synergistically potentiates the deoxycholate-mediated induction of COX-2 expression. PHY2, Aug 2014; 2: e12143.
Alarab et al., Expression of Extracellular Matrix-Remodeling Proteins Is Altered in Vaginal Tissue of Premenopausal Women With Severe Pelvic Organ Prolapse. Reproductive Sciences, Jun 2014; 21: 704 - 715.
Keiichiro Mishima et al., Involvement of N-type Ca2+ channels in the fibrotic process of the kidney in rats. Am J Physiol Renal Physiol, Mar 2013; 304: F665 - F673.
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