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BEC

A potent arginase inhibitor
Catalog #: 2359
SKU-Size Size Price Qty
2359-1 1 mg
$55.00
2359-5 5 mg
$220.00
More Sizes Get Quote

Product Details

Alternate Name S-​(2-​boronoethyl)-​L-​cysteine
Appearance White solid
CAS # 63107-40-4
Molecular Formula C₅H₁₂BNO₄S
Molecular Weight 193.03
Purity ≥98%
Solubility PBS, pH 7.2 (~ 5 mg/ml)
SMILES B(CCSCC(C(=O)O)N)(O)O
InChi InChI=1S/C5H12BNO4S/c7-4(5(8)9)3-12-2-1-6(10)11/h4,10-11H,1-3,7H2,(H,8,9)/t4-/m0/s1
InChi Key OTJHLDXXJHAZTN-BYPYZUCNSA-N
PubChem CID 9877608
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent, slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 µM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 µM and 30 nM at pH 7.5 and 9.5, respectively. It does not inhibit murine iNOS at concentrations up to 1 mM. BEC significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM.


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