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Beauvericin

An enniatin mycotoxin inducing apoptosis and having cytotoxic properties
Catalog #: B1246
SKU-Size Size Price Qty
B1246-1 1 mg
$85.00
B1246-5 5 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]
Appearance White to off-white solid
CAS # 26048-05-5
Molecular Formula C₄₅H₅₇N₃O₉
Molecular Weight 783.96
Purity ≥97% by HPLC
Solubility DMSO(>19 mg/ml)
SMILES CC(C)C1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC2=CC=CC=C2)C)C(C)C)CC3=CC=CC=C3)C)C(C)C)CC4=CC=CC=C4)C
InChi InChI=1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3
InChi Key GYSCAQFHASJXRS-UHFFFAOYSA-N
PubChem CID 105014
MDL Number MFCD00056846
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Beauvercin is an enniatin mycotoxin isolated from fungus Beauveria sp. It has shown cytotoxic properties against insect cells SF-9 and induces apoptosis with IC₅₀ value of 4.5 µM. It has shown to affect mitochondria by depleting the transmembrane potential, inducing swelling and decreasing calcium retention capacity.


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