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BCT-197

A potent P38 mitogen-activated protein kinase inhibitor
Catalog #: B3410
SKU-Size Size Price Qty
B3410-5 5 mg
$135.00
B3410-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name 3-(5-amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl)-N-cyclopropyl-4-methylbenzamide Acumapimod
Appearance Solid
CAS # 836683-15-9
Molecular Formula C₂₂H₁₉N₅O₂
Molecular Weight 385.43
Purity ≥98%
Solubility >25 mg/ml DMSO
SMILES O=C(NC1CC1)C2=CC=C(C)C(N3N=CC(C(C4=CC=CC(C#N)=C4)=O)=C3N)=C2
InChi InChI=1S/C22H19N5O2/c1-13-5-6-16(22(29)26-17-7-8-17)10-19(13)27-21(24)18(12-25-27)20(28)15-4-2-3-14(9-15)11-23/h2-6,9-10,12,17H,7-8,24H2,1H3,(H,26,29)
InChi Key VGUSQKZDZHAAEE-UHFFFAOYSA-N
PubChem CID 11338127
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BCT-197 is an oral p38 MAP kinase inhibitor and an anti-inflammatory agent. The p38 protein kinases, in particular p38α and p38β, regulate the production of multiple inflammatory mediators.


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