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Bcl-2 Antibody

based on 2 citations in multiple journalsBcl-2 Antibody24.1 4
Catalog #: 3033
SKU-Size Size Price Qty
3033-30T 30 µg
$89.00
3033-100 100 µg
$290.00
More Sizes Get Quote

Product Details

Antibody Target Bcl-2
Alternate Name BCL2, BCL 2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to the N-terminus of human Bcl-2
Accession # M13994
Gene ID 596
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit anti-Bcl-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml), Immunoprecipation (4-8 µg/ml), and Immunohistochemistry (10-20 µg/ml). Detects a 25 kDa protein, corresponding to the apparent molecular weight of the ⍺ isoform of Bcl-2 on SDS-PAGE immunoblots.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Bcl-2 and its homologs belong to a family of proteins that either promotes or prevent apoptosis. Bcl-2 alpha and beta are the alternatively spliced isoforms of 25 kDa and 22 kDa mitochondrial integral membrane proteins that inhibit apoptosis.


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Jean-François Guérin et al., Subcellular dynamics of the maternal cell death regulator BCL2L10 in human preimplantation embryos. Hum. Reprod., Mar 2013; 28: 729 - 739.
Giuliani, D., et al. (2005) Endocrinology 10-1210/en.2005-0692.
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