Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

BBT-594

A potent and selective RET and JAK2 inhibitor.
Catalog #: B2114
SKU-Size Size Price Qty
B2114-5 5 mg
$135.00
B2114-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name 5-((6-acetamidopyrimidin-4-yl)oxy)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)indoline-1-carboxamide; NVP-BBT594
Appearance White to off-white solid
CAS # 882405-89-2
Molecular Formula C₂₈H₃₀F₃N₇O₃
Molecular Weight 569.59
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC(=O)NC1=CC(=NC=N1)OC2=CC3=C(C=C2)N(CC3)C(=O)NC4=CC(=C(C=C4)CN5CCN(CC5)C)C(F)(F)F
InChi InChI=1S/C28H30F3N7O3/c1-18(39)34-25-15-26(33-17-32-25)41-22-5-6-24-19(13-22)7-8-38(24)27(40)35-21-4-3-20(23(14-21)28(29,30)31)16-37-11-9-36(2)10-12-37/h3-6,13-15,17H,7-12,16H2,1-2H3,(H,35,40)(H,32,33,34,39)
InChi Key VQLNKQZLPGLOSI-UHFFFAOYSA-N
PubChem CID 59596344
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BBT-594 is a potent and selective RET and JAK2 inhibitor. It impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells. Displays potent anticancer activity.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.