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Bazedoxifene acetate

A selective estrogen receptor modulator (SERM)
Catalog #: B3245
SKU-Size Size Price Qty
B3245-5 5 mg
B3245-25 25 mg
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Product Details

Alternate Name TSE-424 acetate; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate
Peptide Sequence N/A
Appearance White solid
CAS # 198481-33-3
Molecular Formula C₃₀H₃₄N₂O₃.C₂H₄O₂
Molecular Weight 530.65
Purity ≥98% by HPLC
Solubility >40 mg/ml DMSO
InChi InChI=1S/C30H34N2O3.C2H4O2/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31;1-2(3)4/h6-15,20,33-34H,2-5,16-19,21H2,1H3;1H3,(H,3,4)
PubChem CID 154256
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Bazedoxifene acetate (TSE-424 acetate) is a nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.

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