Product Details
| Cat # +Size | 2027-1 |
|---|---|
| Size | 1 mg |
| Alternate Name | 4-((4-carboxybutyl)(2-((4-phenethylbenzol)- oxy)phenethyl)amino)methyl(benzoic) acid; BAY582667; cinaciguat |
| Appearance | White solid |
| CAS # | 1240669-95-7 |
| Molecular Formula | C₃₆H₃₉NO₅.HCl |
| Molecular Weight | 602.16 |
| Purity | ≥98% by NMR |
| Solubility | DMSO |
| SMILES | C1=CC=C(C=C1)CCC2=CC=C(C=C2)COC3=CC=CC=C3CCN(CCCCC(=O)O)CC4=CC=C(C=C4)C(=O)O.Cl |
| InChi | InChI=1S/C36H39NO5.ClH/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28;/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41);1H |
| InChi Key | LLHMBJOVHATVSP-UHFFFAOYSA-N |
| PubChem CID | 10031513 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Displays potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity.
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Sharifi-Sanjani et al., Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+-CaMKII-Regulated Induction of HDAC3. JAHA, Jun 2014; 3: e000670.
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