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BAY 58-2667 Hydrochloride

based on 1 citations in multiple journalsBAY 58-2667 Hydrochloride14.1 4
A guanylyl cyclase activator
Catalog #: 2027

In stock

$295.00

Product Details

Cat # +Size 2027-1
Size 1 mg
Alternate Name 4-((4-carboxybutyl)(2-((4-phenethylbenzol)- oxy)phenethyl)amino)methyl(benzoic) acid; BAY582667; cinaciguat
Appearance White solid
CAS # 1240669-95-7
Molecular Formula C₃₆H₃₉NO₅.HCl
Molecular Weight 602.16
Purity ≥98% by NMR
Solubility DMSO
SMILES C1=CC=C(C=C1)CCC2=CC=C(C=C2)COC3=CC=CC=C3CCN(CCCCC(=O)O)CC4=CC=C(C=C4)C(=O)O.Cl
InChi InChI=1S/C36H39NO5.ClH/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28;/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41);1H
InChi Key LLHMBJOVHATVSP-UHFFFAOYSA-N
PubChem CID 10031513
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Displays potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity.


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Sharifi-Sanjani et al., Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca2+-CaMKII-Regulated Induction of HDAC3. JAHA, Jun 2014; 3: e000670.
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