Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

BAX Activator, BAM7

A potent and selective BAX activator
Catalog #: 2451
SKU-Size Size Price Qty
2451-5 5 mg
2451-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Appearance Brown solid
CAS # 331244-89-4
Molecular Formula C₂₁H₁₉N₅O₂S
Molecular Weight 405.47
Purity ≥98% by HPLC
Solubility DMSO (~ 2 mg/ml)
InChi InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+
PubChem CID 5754137
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent and selective BAX activator (EC₅₀ = 3.3 μM). BAM7 directly binds at the BH3-binding site; selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. BAM7 selectively induces BAX-mediated apoptosis by triggering the hallmark features of intracellular BAX activation. BAM7 only kills the cell line that contains BAX, eliciting the biochemical and morphologic features of BAX-mediated apoptosis.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.