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A potent and selective JAK1 and JAK2 inhibitor
Catalog #: 2842
SKU-Size Size Price Qty
2842-10 10 mg
2842-50 50 mg
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Product Details

Alternate Name 2-[1-Ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile; INCB 028050;LY 3009104;INCB028050;LY3009104;LY-3009104;INCB-028050
Appearance White to off-white solid
CAS # 1187594-09-7
Molecular Formula C₁₆H₁₇N₇O₂S
Molecular Weight 371.42
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
InChi InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
PubChem CID 44205240
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2.

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