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Anti-BAR2 Antibody (S261)

Polyclonal antibody against EDG5
Catalog #: A1057
$265.00

Product Details

Cat # +Size A1057-100
Size 100 µg
Antibody Target BAR2
Alternate Name Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH conjugated synthetic peptide between 236-264 amino acids from human BAR2
Accession # P07550
Gene ID 154
Appearance Colourless liquid
Concentration 1 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Species Reactivity Human, Mouse
Application Western blot, IHC
Positive Control Western blot, IHC
Application & Usage WB: 1:1000, IHC: 1:50~101
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.


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