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Baicalein

A potent inhibitor of 5- and platelet 12-lipoxygenases
Catalog #: B2309

In stock

SKU-Size Size Price Qty
B2309-50 50 mg
$75.00
B2309-250 250 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name 5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one
Appearance Yellow solid
CAS # 491-67-8
Molecular Formula C₁₅H₁₀O₅
Molecular Weight 270.24
Purity ≥98%
Solubility DMSO (>10 mg/ml)
SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)O)O
InChi InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChi Key FXNFHKRTJBSTCS-UHFFFAOYSA-N
PubChem CID 5281605
MDL Number MFCD00017459
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Baicalein inhibits lipid peroxidation, as assessed by production of thiobarbituric acid (TBARS; IC₅₀= 5 µM), and inhibits growth of Huh-7, KIM-1, and HLF human hepatocellular carcinoma cells (IC₅₀s = 17-70 µg/ml).


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